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  Home > Books & CD's > Books - By Dr. Constantini Fungalbionic Series >

  Prostate Cancer - Hope At Last Book (FungalBionics)
  Fungalbionics Prostate Cancer
Fungalbionics Prostate Cancer
  
List Price: $55.00
Our Price: $55.00


Product Code: FBS-PC


Description
 
The Fungal/Mycotoxin Etiology of Prostate Cancer
Foods That Cause & Foods That Pvevent
522 Pages - 900 Refs.

Excerpt:



FUNGI/MYCOTOXINS
ARE THE CAUSE OF
PROSTATE CANCER
 Chapter 29
CYCLOSPORIN CAUSES PROSTATE CANCER
 

CYCLOSPORIN IS A MYCOTOXIN

CYCLOSPORIN CAUSES PROSTATE CANCER

CYCLOSPORIN ENHANCES METASTASIS
OF PROSTATE CANCER CELLS
 

THE REPORTED CLINICAL FACTS

Cyclosporin Is A Mycotoxin

Betina (1989) points out that cyclosporin is actually a mycotoxin, a fungal-derived secondary metabolite which is toxic to the immune system.
 

Cyclosporin Causes Prostate
Cancer In Liver Transplantation Patients

Frezza et al. (1997) noted that the increasing length of survival of organ transplant recipients necessitates careful attention to the potential neoplastic complications of life-long immunosuppression which is required for such patients. Previous studies of patients taking triple drug therapy (cyclosporin, azathioprine and prednisone) for immunosuppression have shown a high percentage of tumor development
(3,117 per 2,915 patients).

3,394 adult patients underwent orthotopic liver transplantation at the University of Pittsburgh Medical Center, Transplant Institute prior to December 1992.

A total of 50 patients with tumors were identified (37 males, 13 females), ranging between 34 and 69 years of age. The types of cancers caused by cyclosporin included prostate cancer.
 

Cyclosporin Causes Prostate
Cancer In Renal Transplant Patients

Voght (1990) analyzed a population of renal transplant recipients treated with cyclosporin and prednisolone with respect to clinically evident de novo malignancies.

Eighteen of 598 patients (mean age 35.6 (1-73) years receiving their first renal graft between May, 1981 and December, 1986 developed a malignancy at a mean interval of 33.5 months.

The types of cancers caused by cyclosporin included carcinoma of the prostate.
 

THE REPORTED ANIMAL STUDIES

The Mycotoxin Cyclosporin Enhances
Metastasis Of Prostate Cancer Cells In Rats

Pollard (1997) reported that the rate and extent of metastasis by prostate adenocarcinoma cells was enhanced in rats by the administration of cyclosporin A. The cancer cells spread through the lymph nodes to the lungs in which they developed secondary tumors.
 

 Chapter 30
AFLATOXIN AS A MYCOTOXIN CAUSE OF PROSTATE CANCER
 

AFLATOXIN-CONTAMINATED
FOODS CAUSE PROSTATE CANCER
 
AFLATOXIN CAUSES P53 MUTATION
AS FOUND IN PROSTATE CANCER
 

THE REPORTED CLINICAL FACTS

Aflatoxin-Contaminated
Foods Cause Prostate Cancer

The various foods which are documented to cause prostate cancer share little in common except that they are all high on the list of fungal/mycotoxin-contaminated foods. The carcinogenic mycotoxin most often encountered is aflatoxin. The possibility that this is a matter of coincidence is unlikely, particularly when it has been documented that aflatoxin causes mutation of normal rat prostate cells (Link et al. [1983]). One must read this chapter in the light of the fact that the cause of prostate cancer has been previously deemed to be unknown.

To learn about the foods most frequently found to be contaminated with aflatoxin which are associated with an increased risk of men developing prostate cancer, see the pertinent food chapters in Part VI.
 

The p53 Gene Mutation Is Caused By Aflatoxin

In his 1995 Deichmann Lecture presentation, Harris provides an update of the genetic aspects of cancer. Cancer is a multistage process involving the activation of proto-oncogenes, for example ras, and the inactivation of tumor suppressor genes, such as p53 and p16INK4.

Harris points out that p53 is a prototype tumor suppressor gene that is the most common genetic lesion in human cancers including prostate cancer.

In 1991, Harris stated that the p53 mutation is found in hepatocellular carcinomas from both Qidong, People's Republic of China and southern Africa. Harris continues:

"This observation links exposure to aflatoxin, a known cancer risk factor in these geographic regions, with a specific mutation in a cancer-related gene."

Simply stated, the mutation found in the p53 gene is due to a mycotoxin. (See also Lilleberg [1992].)
 

THE REPORTED ANIMAL STUDIES

Aflatoxin Mycotoxin Causes Mutations (Pre-
Cancerous Change) In Normal Rat Prostate Cells

Link et al. (1983) reported that aflatoxin increased the frequency of mutants in normal rat prostate cells.

It was concluded that their procedures now make it possible to detect some environmental carcinogens likely to cause prostate cancer by virtue of their ability to mutate cultured rat prostate epithelial cells.

The sensitivity of the rat prostate cells cell line to aflatoxin-induced cytotoxicity and mutagenesis also makes it a useful cell system in which to study enzymes governing the conversion of aflatoxin to gene-toxic metabolites. See also Soderkvist et al. (1983).

  Chapter 29
ZERALENONE CAUSES PROSTATE CANCER
 

ZEARALENONE IS A MYCOTOXIN

ZEARALENONE DERIVATIVE ZERANOL
CAUSES PRECANCEROUS METAPLASIA

ZERANOL IS USED AS A FATTENING
AGENT IN LIVESTOCK ANIMALS
 

Zeranol is a derivative of the Fusarium mycotoxin zearalenone which is used to artificially fatten domestic animals for human consumption. Such meat contains measurable amounts of this growth promoter and this has raised serious questions relative to endangering the health of meat consumers.

This is particularly worrisome since meat causes prostate cancer in humans (see Chapter 48.).
 

THE REPORTED ANIMAL STUDIES
 
Zeranol (Mycotoxin Zearalenone Derivative) Causes
Pre-Cancerous Metaplasia Of Prostate Cells In Bulls

Deschamps et al. (1987) studied the effects of zeranol on scrotal circumference, serving ability, semen characteristics, and postmortem measurements of the genital organs in beef bulls from 9 to 20 months of age.

Histologic examination of the genital organs revealed that zeranol induced adenomyosis and sperm granulomas in the Caudae epididymidis and markedly altered the structure of the sexual accessory glands of bulls.
Low epithelium associated with focal areas of squamous metaplasia were found to be induced in the prostate of the zeranol-dosed bulls. Metaplasia is generally considered to represent a precancerous change in afflicted tissue cells.

Zeranol Stimulates Growth
Of Prostate Gland In Lambs

Wiggins et al. (1980) found that zeranol stimulates the growth of the seminal vesicles, the prostate gland and the preputial glands in lambs. See also Marois and Marois (1979).
 

Zeranol Causes Hyperplasia And Cellular
Transformations In Prostate Glands Of Sheep

Rothenbacher et al. (1975) reported that zeranol administered to sheep caused hyperplasia (increased growth of number of cells) as well as transitional cell and squamous cell transformation in their prostate glands.




TABLE OF CONTENTS
 
PART I
FUNGI AND MYCOTOXINS

CHAPTER 1 FUNGALBIONIC: FUNGAL TOXINS CAUSE DEGENERATIVE AND CANCEROUS DISEASES  
CHAPTER 2  THE TROJAN HORSE: FUNGI AND MYCOTOXINS ARE IN THE FOOD CHAIN



PART II
FUNGI/MYCOTOXINS ARE THE CAUSE OF MOST CANCERS
CHAPTER 3 THE FUNGAL/MYCOTOXIN ETIOLOGY OF CANCER
CHAPTER 4 FOOD ADDITIVES AND TRACE PESTICIDES DO NOT CAUSE CANCER
CHAPTER 5 NITROSAMINE ETIOLOGY OF CANCER: FUNGAL DERIVED NITROSAMINES
CHAPTER 6 THE VIRAL ETIOLOGY OF CANCER IN HUMANS�AN UNPROVED POSTULATE
CHAPTER 7 AFLATOXIN CAUSES CANCERS IN HUMANS
CHAPTER 8 AFLATOXIN CAUSES NEOPLASMS IN ANIMALS
CHAPTER 9 CYCLOSPORIN CAUSES CANCER IN HUMANS
CHAPTER 10 PENICILLIN AND OTHER FUNGAL-DERIVED ANTIBIOTICS CAUSE LYMPHOMA IN HUMANS
CHAPTER 11 FUNGAL-DERIVED ANTIBIOTICS ARE MYCOTOXINS & CAUSE CANCER IN ANIMALS
CHAPTER 12 FUSARIUM MYCOTOXINS CAUSE CANCER IN HUMANS
CHAPTER 13 FUSARIUM MYCOTOXINS CAUSE HUMAN-TYPE CANCERS IN ANIMALS
CHAPTER 14 OCHRATOXIN CAUSES CANCER IN HUMANS
CHAPTER 15 OCHRATOXIN CAUSES HUMAN-TYPE TUMORS IN ANIMALS
CHAPTER 16 OTHER MYCOTOXINS CAUSE HUMAN-TYPE TUMORS IN ANIMALS
CHAPTER 17 FUNGI CAUSE CANCERS IN HUMANS
CHAPTER 18 FUNGI CAUSE HUMAN-TYPE TUMORS IN ANIMALS
CHAPTER 19 EDIBLE MUSHROOMS CAUSE HUMAN-TYPE CANCERS IN ANIMAL
CHAPTER 20 FUNGAL COLONIZATION OF HOUSES FOUND TO CAUSE LEUKEMIA
CHAPTER 21 CARCINOGENIC FUNGI/MYCOTOXINS ARE FOUND IN TOBACCO
CHAPTER 22 DIET, MYCOTOXINS AND CANCER: INTERACTIONS
CHAPTER 23 DIETARY FATS ENHANCE THE FUNGAL/MYCOTOXIN CANCER POTENTIAL
CHAPTER 24 MEAT, MEAT PRODUCTS, FUNGI, MYCOTOXINS AND RISK OF CANCER
CHAPTER 25 DRIED FISH CAUSES GASTRIC CANCER IN HUMANS
CHAPTER 26 CANCERS CAUSED BY STORED GRAINS
CHAPTER 27 ALCOHOL CAUSES CANCER IN HUMANS /THE MYTH: "ALCOHOL IS GOOD FOR YOU"

 
 
PART III
PROSTATE CANCER: SOME BASIC FACTS

CHAPTER 28 PROSTATE CANCER: HOPE AT LAST

 


PART IV
FUNGAI/MYCOTOXINS ARE THE
CAUSE OF PROSTATE CANCER

CHAPTER 29 CYCLOSPORIN CAUSES BREAST CANCER
CHAPTER 30 AFLATOXIN AS A MYCOTOXIN  
CAUSE OF PROSTATE CANCER
CHAPTER 31 ZEARALENONE CAUSES PROSTATE CANCER
CHAPTER 32 CYTOCHALASIN CAUSES CELLULAR  
CHANGES AS SEEN IN PROSTATE CANCER
CHAPTER 33 FUNGAL NITROSAMINES CAUSE PROSTATE CANCER

 
 
PART V
PROSTATE CANCER MYTHS

CHAPTER 34 GENES DO NOT CAUSE PROSTATE CANCER
CHAPTER 35 TESTOSTERONE DOES NOT  
CAUSE PROSTATE CANCER
CHAPTER 36 HORMONAL TREATMENT DOES NOT CURE PROSTATE CANCER
CHAPTER 37 SURGERY DOES NOT CURE PROSTATE CANCER
CHAPTER 38 CHEMOTHERAPY DOES NOT CURE PROSTATE CANCER
CHAPTER 39 RADIATION THERAPY DOES NOT  
CURE PROSTATE CANCER
CHAPTER 40 PROSTATE SPECIFIC ANTIGEN NOT SPECIFIC FOR PROSTATE CANCER

 
 
PART VI
FOODS WHICH CAUSE PROSTATE CANCER
 CHAPTER 41 MUSHROOMS CAUSE PROSTATE CANCER
CHAPTER 42 ALCOHOL CAUSES PROSTATE CANCER
CHAPTER 43 BEER CAUSES PROSTATE CANCER
CHAPTERS 44-59 OTHER FOODS AND HABITS WHICH  
CAUSE PROSTATE CANCER
 
 
PART VII
VITAMINS AND MINERALS WHICH
PREVENT PROSTATE CANCER

CHAPTER 60 VITAMIN A PREVENTS PROSTATE CANCER
CHAPTER 61 VITAMIN C PREVENTS PROSTATE CANCER
CHAPTERS 62-72 OTHER VITAMINS AND MINERALS  
WHICH PREVENT PROSTATE CANCER



PART VIII
PLANT COMPONENTS PREVENT
PROSTATE CANCER
 CHAPTER 73 PLANT FIBER PREVENTS PROSTATE CANCER
CHAPTER 74 PLANT PECTIN PREVENTS PROSTATE CANCER
CHAPTERS 75-80 OTHER PLANT COMPONENTS WHICH PREVENT PROSTATE CANCER
 
 
PART IX
FOODS WHICH PREVENT
PROSTATE CANCER
 CHAPTER 81 VEGETABLES PREVENT PROSTATE CANCER  
CHAPTER 82 ENDIVE PREVENTS PROSTATE CANCER  
CHAPTER 83 GARLIC PREVENTS PROSTATE CANCER
CHAPTER 84-101 OTHER FOODS WHICH PREVENT  
PROSTATE CANCER
 
 
 
PART X
EXERCISE AND SUNLIGHT
 CHAPTER 102-103 EXCERCISE AND SUNSHINE AS THEY RELATE TOTHE CAUSE AND PREVENTION OF PROSTATE CANCER  
 


PART XI
ANTIFUNGAL DRUGS EFFECTIVE
AGAINST PROSTATE CANCER
 CHAPTER 104 ANTIFUNGAL NATURE OF DRUGS  
AGAINST PROSTATE CANCER
CHAPTER 105 ASPIRIN/SALICYLATES EFFECTIVE AGAINST  
PROSTATE CANCER
CHAPTER 106 KETOCONAZOLE EFFECTIVE AGAINST PROSTATE CANCER  
 
CHAPTER 107 COLCHICINE EFFECTIVE AGAINST PROSTATE CANCER
 CONCLUSION  
REFERENCES  
INDEX
 

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